Neysa Adrienne

Kornblum Oxidation Reaction. The kornblum oxidation is a chemical reaction of a primary halide with dimethyl sulfoxide (dmso) to form an aldehyde. (1959) a primary tosylate is heated at 150 o to cause s n 2 displacement by the oxygen of dimethyl sulfoxide (dmso) in the presence of nahco 3.

To achieve this suppression, an α‑iodo ketone is introduced to undergo a process of kornblum oxidation reaction that releases halide ions. Most recent work has been aimed at.